Prof Nicki Tiffin works in the Division of Computational Biology, and on the Wellcome CIDRI-Africa Data Integration Platform at the University of Cape Town, where my research addresses evidence-based health care through the integration and analysis of complex datasets which cross multiple health research domains, including genomic, clinical and epidemiological data. She also contributes to databasing of patient clinical information, including ethical and data governance requirements, at the Provincial Health Data Centre in the Western Cape Department of Health, South Africa. Her experience in molecular genetics, bioinformatics and epidemiology guides her research in exploring the ethical use and analysis of large health genomics datasets to improve health outcomes Prof Nicola Mulder heads the Computational Biology Division at the University of Cape Town, and leads H3ABioNet, a large Pan African Bioinformatics Network of ~30 institutions in 17 countries. H3ABioNet aims to develop bioinformatics capacity to enable genomic data analysis on the continent. Prior to her position at UCT, she worked for 9 years at the European Bioinformatics Institute in Cambridge, as a Team Leader. At UCT her research focuses on genetic determinants of susceptibility to disease, African genome variation, and microbial genomics and infectious diseases from both the host and pathogen perspectives. Her group provides bioinformatics services and develops new algorithms for the analysis of complex African genetic data. Prof Mulder is actively involved in training and education as well as curriculum development in Bioinformatics and Genomic Medicine. Dr Jennifer Mabuka works under the programmatic arm of the African Academy of Sciences that focuses on improving the research and development landscape on the African continent. She oversees the Human Heredity and Health in Africa programme and is also a programme consultant for the Clinical Trial Community. Previously, she spent 16 years doing HIV-1 clinical research focused on correlates of protection in mother to child transmission of HIV-1. She holds a PHD from the University of Washington`s Department of Global Health and spent 3 years as a postdoctoral fellow with the Ragon Institute of NGH, MIT and Harvard and KwaZulu Natal Research Institute for TB and HIV (KRITH). She is Currently a Clinical Associate Professor at the University of Washington in Seattle and a 2018 Aspen New Voices Fellow.